Zoo tshaj Vinpocetine hmoov (42971-09-5) Chaw tsim tshuaj paus

Vinpocetine hmoov

Kaum ib hlis 5, 2020

Cofttek yog qhov zoo tshaj plaws Vinpocetine hmoov chaw tsim tshuaj paus hauv Suav teb. Peb lub Hoobkas muaj kev tswj hwm kev tsim khoom tiav (ISO9001 & ISO14001), nrog lub peev xwm tsim khoom txhua hli ntawm 340kg.

raws li txoj cai: Hauv Pawg Ntau Lawm
Chav: 1kg / hnab, 25kg / Nruas

Vinpocetine hmoov Specifications

Lub npe: Vinpocetine
CAS: 42971-09-5
purity 98%
Cov mis qauv: C22H26N2O2
Lub cev nyhav: 350.454 g / mol
Melt Point: 147-149 ° C
Tshuaj lub npe: AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate,
txhais: Ethyl Ester, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine.
Qhov tseem ceeb hauv InChI: DDNCQMVWWZOMLN-IRLDBZIGSA-N
Tshem Tawm Ib Nrab Lub Neej: 2.54 +/- 0.48 teev
Dej Cev: Soluble hauv DMSO, Methanol, Dej
Cia Kev Mob: 0 - 4 C rau lub sij hawm luv (hnub rau lis piam), lossis -20 C rau lub sij hawm ntev (hli)
daim ntawv thov: Vinpocetine yog qhov sib txuas los ntawm Periwinkle cog uas yog siv los ua tus neeg paub tab thiab tiv thaiv kev laus. Ib qho ntawm cov muaj ntau ntawm cov nootropics, Vinpocetine tuaj yeem txhim kho cov ntshav thiab muaj peev xwm ua kom lub cim xeeb nce ntxiv; qhov kev thov kawg no tseem tsis tau raug tshawb xyuas.
tsos: Dawb hmoov

 

Vinpocetine (42971-09-5) NMR Spectrum NPE

Vinpocetine (42971-09-5)-NMR Spectrum

Yog tias koj xav tau COA, MSDS, HNMR rau txhua qhov khoom seem thiab lwm yam ntaub ntawv, thov hu rau peb tus thawj tswj kev lag luam.

 

Vinpocetine yog dab tsi (42971-09-5)?

Vinpocetine yog ib qho hluavtaws alkaloid muab tau los ntawm tsob ntoo periwinkle (tshwj xeeb, sib cais los ntawm cov qauv hu ua 'vincamine') uas pom tias muaj cov ntaub ntawv teev tseg txog kev siv nyob rau hauv European lub teb chaws rau kev kho mob ntawm lub hlwb, poob rov qab, thiab mob vwm. Vinpocetine kuj tseem siv tau los ua cov chaw nootropic nyob rau hauv kev cia siab tias nws yuav txhawb txoj kev nco.

 

Vinpocetine hmoov (42971-09-5) cov txiaj ntsig

Vinpocetine tsis yog kev nkag siab, tab sis dab tsi yog nqus peaks hauv cov ntshav sai thiab nkag mus rau hauv lub hlwb qhov twg nws tuaj yeem siv nws txoj haujlwm. Cov khoom uas tshwm sim siv rau qhov ncauj vinpocetine ntxiv muaj xws li neuroprotection (tawm tsam co toxins thiab kev tshaj tawm) thiab txo cov leeg mob, qhov tseem ceeb ntawm lub peev xwm tsis pom zoo muaj kev txhawb nqa zoo los ntawm cov pov thawj hauv lub sijhawm no. Thaum vinpocetine pom tau tias muaj txiaj ntsig zoo hauv kev tiv thaiv cov co toxins lossis kev nyuaj siab los ntawm kev ua rau amnesia, nws tseem tsis tau pom tias ua kom txhim kho kev nco.

Vinpocetine kuj tseem pom tias muaj qee qhov kev ua tau zoo rau qhov kev txawj ntse poob qis, tab sis cov ntaub ntawv ntawm cov ncauj lus no muaj tsawg dua li lwm cov tshuaj sim rau lub hom phiaj no (CDP-Choline lossis Alpha-GPC) tshwj xeeb. Tsawg kawg ntawm ib txoj kev tshawb nrhiav tau sau tseg txog kev txhim kho hauv lub sijhawm cov tshuaj tiv thaiv nrog 40mg ntsiav tshuaj ntawm vinpocetine, uas tej zaum yuav yog ib qho tsuas yog txhim kho rau cov tib neeg muaj kev noj qab haus huv nyob rau lub sijhawm tam sim no.

Txoj kev kho mob vinpocetine tshwm sim los txhim kho cov ntshav txaus rau lub hlwb yam tsis muaj kev hloov kho lub zog kom muaj zog, thiab qhov no yog kev xav (tab sis tsis qhia) siv rau kev noj ntawm qhov ncauj. Qhov no yuav muaj peev xwm txo kev mob taub hau los ntawm kev kub siab dhau, thiab yog raws li kev siv ib txwm muaj ntawm cov ntoo periwinkle (kom txo tau mob taub hau).

 

Vinpocetine (42971-09-5) Daim ntawv thov?

Cov txheej txheem ntawm vinpocetine muaj ntau. Nws zoo nkaus li cuam tshuam nrog ntau lub ion channel (sodium, potassium, thiab calcium) thaum nyhav ua rau muaj kev cuam tshuam los ntawm neurotransmitter tso tawm thiab neuroprotection thaum dopamine lossis glutamate yog suppressed (ob qhov no, thaum tsis tsim nyog tsa los ntawm co toxins, tuaj yeem ua rau oxidative puas tsuaj). Nws tseem cuam tshuam nrog alpha adrenergic receptors thiab TPSO receptor, thiab thaum lub txiaj ntsig zoo ntawm cov kev sib cuam tshuam cov receptor tsis paub meej lawv yuav muaj feem cuam tshuam txij li thaum lawv tshwm sim nyob rau tib qho kev cuam tshuam uas cov ion channel sib cuam tshuam.

Vinpocetine tseem yog PDE1 inhibitor, uas yog ib qho tshuab uas yog ob qho tib si cardioprotective thiab kev txhim kho kom pom. Hmoov tsis zoo, qhov kev cuam tshuam no tshwm sim ntawm kev txiav txim ntau thiab tej zaum yuav tsis siv rau cov tshuaj ntxiv ntawm vinpocetine.

Zoo ib yam li PDE1, ib qho tshuaj tiv thaiv muaj peev xwm ntawm vinpocetine thiab kev cuam tshuam ncaj qha ntawm glutaminergic receptors ob qho tib si tshwm sim thaum muaj kev kub siab ntau hauv vitro thiab tej zaum yuav tsis cuam tshuam nrog cov qauv ntxiv.

 

Vinpocetine (42971-09-5) ntau npaum

Vinpocetine tau noj nyob rau hauv ntau npaum li cas txhua hnub ntawm 15-60mg, muab faib ua peb zaug tshuaj txhua hnub nrog zaub mov noj. Tus txheej txheem qis koob tshuaj yog 5mg ntawm txhua ntawm peb pluas noj no, nrog 20mg ntawm txhua pluas noj tau pom tias qhov kev ua tau zoo dua qub. Cov koob tshuaj no yog noj rau lub hom phiaj ntawm neuroprotection, ua kom cov ntshav hlwb khiav lag luam, thiab ua kom cov lej poob qis.

Cov koob tshuaj nyob hauv qhov siab dua qhov kawg ntawm qhov (30-45mg mob me me) yuav pab tau zoo rau kev nthuav qhia kev txawj ntse thiab cim xeeb hauv cov neeg muaj kev noj qab haus huv, tab sis tsis muaj ntau cov pov thawj saib ntawm qhov kev thov no.

Ceeb Toom: rau cov poj niam cev xeeb tub, qhov sib npaug ntawm cov koob tshuaj abouve 10 mg / d tau cuam tshuam nrog kev mob plab me nyuam hauv kev kawm tsiaj. 10 mg / d kuj tseem yuav muaj kev pheej hmoo, tshwj xeeb tshaj yog thaum noj thoob plaws thaum cev xeeb tub.

 

Vinpocetine hmoov kev muag khoom(Qhov twg Yuav Vinpocetine hmoov hauv qhov loj)

Peb lub tuam txhab txaus siab rau kev sib raug zoo ntev nrog peb cov neeg vim tias peb tsom mus rau cov neeg siv khoom thiab muab cov khoom zoo. Yog tias koj txaus siab rau peb cov khoom lag luam, peb yoog tau nrog kho kom haum cov kev txiav txim siab kom haum koj cov kev xav tau tshwj xeeb thiab peb lub sijhawm ceev ceev ntawm kev txiav txim tau lees tias koj yuav tau saj zoo peb cov khoom kom raws sijhawm. Peb kuj tseem tsom rau kev pabcuam ntxiv tus nqi. Peb muaj nyob rau cov lus nug kev pabcuam thiab cov ntaub ntawv los txhawb koj txoj kev lag luam.

Peb yog tus kws tshaj lij Vinpocetine hmoov tsum tau ntau xyoo, peb muab cov khoom lag luam nrog cov nqi sib tw, thiab peb cov khoom yog qhov ua tau zoo tshaj plaws thiab yauv nruj, kev sim ywj siab kom ntseeg tau tias nws muaj kev nyab xeeb rau noj thoob ntiaj teb.

 

References
  1. Abdel-Salam OME. Vinpocetine thiab piracetam pheev tiv thaiv antinociceptive cov nyhuv hauv visceral mob qauv hauv cov nas. Cov Tshuaj Kho Mob 2006; 58 (5): 680-691.17085860
  2. Akopov SE, Gabrielian ES. Qhov cuam tshuam ntawm cov tshuaj aspirin, dipyridamole, nifedipine thiab Cavinton uas ua rau platelet aggregation ntxias los ntawm cov neeg sawv cev sib txawv ib leeg thiab hauv kev sib xyaw. Eur J Clin Tshuaj Kho Mob. Xyoo 1992; 42 (3): 257-259.1577042
  3. Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK. Vinpocetine thiab pyritinol: tus qauv tshiab rau ntshav rheological tes taws hauv cerebrovascular cuam tshuam - kev tshawb nrhiav soj ntsuam nyob rau hauv kev soj ntsuam. Biomed Res Int. Xyoo 2014; 2014: 324307.25548768.

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