Alpha Lipoic Acid (ALA)

Plaub Hlis Ntuj 20, 2021

Cofttek yog qhov zoo tshaj Alpha Lipoic Acid (ALA) hmoov chaw tsim tshuaj paus hauv Suav teb. Peb lub Hoobkas muaj kev ua tiav kev tswj hwm kev tsim khoom (ISO9001 & ISO14001), nrog lub peev xwm tsim khoom txhua hli ntawm 1000kg.

 


raws li txoj cai: Hauv Pawg Ntau Lawm
Chav: 1kg / hnab, 25kg / Nruas

Alpha Lipoic Acid (ALA) (1077-28-7) Specifications

Lub npe: Alpha Lipoic Acid (ALA)
CAS: 1077-28-7
purity 98%
Cov mis qauv: C8H14O2S2
Lub cev nyhav: 206.33 g / mol
Melt Point: 60–62 ° C (140–144 ° F; 333–335 K)
Tshuaj lub npe: (R) -5- (1,2-Dithiolan-3-yl) pentanoic acid;

α-Lipoic acid; Alpha lipoic acid; Thioctic acid; 6,8-Dithiooctanoic acid

txhais: (±) -α-Lipoic acid, (±) -1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL -α-Lipoic acid, DL -6,8-Thioctic acid, Lip (S2 )
Qhov tseem ceeb hauv InChI: AGBQKNBQESQNJD-UHFFFAOYSA-N
Ib nrab neej: Ib nrab neej ntawm kev hais lus rau ALA tsuas yog 30 min xwb
Dej Cev: Sollyly So Soluble hauv dej (0.24 g / L); Kev daws mob hauv ethanol 50 mg / mL
Cia Kev Mob: 0 - 4 C rau lub sij hawm luv (hnub rau lis piam), lossis -20 C rau lub sij hawm ntev (hli)
daim ntawv thov: Alpha-lipoic acid yog siv nyob rau hauv lub cev txhawm rau rhuav cov carbohydrates thiab ua lub zog rau lwm lub plab hauv lub cev. Alpha-lipoic acid zoo li ua haujlwm ua cov tshuaj tiv thaiv kab mob, uas txhais tau tias nws yuav muaj kev tiv thaiv rau lub hlwb raws li cov xwm txheej ntawm kev puas tsuaj lossis raug mob.
tsos: Daj koob-zoo li muaju

 

Alpha Lipoic Acid (ALA) (1077-28-7) NMR Spectrum NPE

 

Alpha Lipoic Acid (ALA) (1077-28-7)-NMR Spectrum

Yog tias koj xav tau COA, MSDS, HNMR rau txhua qhov khoom seem thiab lwm yam ntaub ntawv, thov hu rau peb tus thawj tswj kev lag luam.

 

Alpha Lipoic Acid (ALA) (1077-28-7)?

Alpha-lipoic acid yog qhov sib txuam pom nyob sab hauv txhua lub cell ntawm tib neeg lub cev. Nws lub luag haujlwm tseem ceeb yog los hloov cov piam thaj hauv ntshav (cov piam thaj) mus rau lub zog uas siv cov pa oxygen, cov txheej txheem hu ua aerobic metabolism. Alpha-lipoic acid tseem suav tias yog tshuaj tua kab mob antioxidant, txhais tau tias nws tuaj yeem tiv thaiv cov teeb meem sib txuas hu ua dawb radicals uas ua rau cov hlwb puas ntawm cov qib raws roj ntsha.

Dab tsi ua rau alpha-lipoic acid thiaj li tsis zoo yog tias nws yog soluble hauv dej thiab rog. Qhov ntawd txhais tau hais tias nws tuaj yeem xa hluav taws xob tam sim ntawd lossis chaw rau khoom rau siv rau yav tom ntej.

Alpha-lipoic acid kuj tseem tuaj yeem rov qab siv "siv" tshuaj tua kab mob antioxidant, nrog rau cov vitamin C, vitamin E, thiab cov amino acid muaj zog lub npe hu ua glutathione.1 Thaum twg cov antioxidant tsis cuam tshuam cov dawb radical, lawv destabilize thiab ua dawb radicals lawv tus kheej. Alpha-lipoic acid pab kho lawv los ntawm kev nqus cov hluav taws xob ntau dhau thiab hloov mus rau tom qab los ua lawv daim ntawv ruaj khov.

Alpha-lipoic acid qee zaum noj raws li kev pab txhawb ntxiv nyob rau hauv qhov kev cia siab nws tuaj yeem txhim kho qee yam kev ua haujlwm hauv lub cev, nrog rau cov rog rog, collagen ntau lawm, thiab ntshav qabzib tswj. Muaj ntau cov pov thawj uas tsawg kawg ntawm qee qhov kev thov.

 

Alpha Lipoic Acid (ALA) (1077-28-7) cov txiaj ntsig

Mob ntshav qab zib

Nws tau ntev tau xav tias alpha-lipoic acid tuaj yeem pab tswj tau cov piam thaj los ntawm kev nce nrawm nrawm uas cov ntshav qab zib tau metabolized. Qhov no tuaj yeem pab kho mob ntshav qab zib tau, tus kab mob ntshav lub cev tsis muaj ntshav qabzib.

Xyoo 2018 kev tshuaj xyuas thiab meta-tsom xam los ntawm 20 txoj kev tswj hwm kev soj ntsuam ntawm cov neeg muaj teeb meem metabolic (qee yam muaj ntshav qab zib hom 2, lwm tus muaj lwm yam teeb meem metabolic) pom tias lipoic acid supplementation ua rau txo qis ntshav qabzib, insulin concentration, insulin tsis kam, thiab ntshav hemoglobin. A1C qib.

 

Tsom Mob

Neuropathy yog lo lus siv kho mob siv los piav qhia qhov mob, loog, thiab txawv txav los ntawm kev puas siab puas ntsws. Feem ntau, qhov kev puas tsuaj yog tshwm sim los ntawm oxidative kev nyuaj siab tso rau ntawm cov leeg ntshav los ntawm cov kab mob xws li mob ntshav qab zib, mob Lyme, yoov, mob qog, mob raum, thiab HIV.

Nws ntseeg tau los ntawm qee qhov tias alpha-lipoic acid, muab rau hauv cov tshuaj loj txaus, tuaj yeem tiv thaiv qhov kev ntxhov siab no los ntawm kev ua kom muaj zog cov tshuaj antioxidant. Nws tau muaj pov thawj ntawm cov nyhuv no hauv cov neeg muaj ntshav qab zib mob neuropathy, qhov muaj peev xwm txo qis cov neeg muaj ntshav qab zib siab heev.

Kev tshuaj xyuas xyoo 2012 ntawm cov kev tshawb fawb los ntawm Netherlands xaus lus tias ib hnub 600-mg txhaj tshuaj alpha-lipoic acid tau muab tshaj peb lub lis piam muab "tseem ceeb thiab thaj chaw kho mob txo cov neuropathic mob."

Ib yam li cov kev tshawb fawb txog ntshav qab zib dhau los, qhov ncauj tshuaj alpha-lipoic acid feem ntau tsis tshua muaj txiaj ntsig lossis tsis muaj kev cuam tshuam dab tsi.

 

poob

Alpha-lipoic acid lub peev xwm los txhim kho cov roj calorie thiab txhawb kev poob phaus tau dhau los ntawm ntau cov zaub mov gurus thiab cov tuam txhab tsim khoom lag luam. Nrog rau qhov tau hais tias, muaj ntau cov pov thawj uas pom tias alpha-lipoic acid tuaj yeem cuam tshuam rau qhov hnyav, txawm hais tias tsawg.

Kev tshuaj xyuas 2017 ntawm kev tshawb fawb los ntawm Yale University pom tias alpha-lipoic acid pab, thaj tsam li ntawm 300 txog 1,800 mg ib hnub, pab ua rau qhov hnyav hnyav nruab nrab ntawm 2.8 phaus piv rau cov placebo.

Tsis muaj kev sib koom ua ke ntawm alpha-lipoic ntxiv koob tshuaj thiab qhov hnyav ntawm qhov poob phaus. Ntxiv mus, lub sijhawm kho tau zoo rau tus neeg lub cev qhov ntsuas (BMI), tab sis tsis yog tus neeg qhov hnyav.

Qhov no txhais tau li cas yog tias, thaum nws zoo nkaus li koj tuaj yeem tsuas yog poob ntau heev nrog alpha-lipoic acid, koj lub cev muaj pes tsawg leeg tuaj yeem ua kom zoo li rog yog hloov maj mam los ntawm cov nqaij ntshiv.

 

Cov Roj (Cholesterol) siab

Alpha-lipoic acid tau ntseeg ntev dhau los ua qhov hnyav thiab noj qab haus huv los ntawm kev hloov cov lipid (rog) muaj pes tsawg leeg hauv cov ntshav. Qhov no suav nrog kev txhim kho cov lipoprotein (HDL) cov roj (cholesterol) kom ntau thaum cov roj lipoprotein (LDL) roj tsawg dua thiab cov roj triglycerides. Cov kev tshawb fawb tsis ntev los no qhia tias qhov no yuav tsis yog li ntawd.

Hauv kev tshawb nrhiav xyoo 2011 los ntawm Kauslim, 180 tus neeg laus tau muab 1,200 rau 1,800 mg ntawm alpha-lipoic acid poob 21 feem pua ​​cov nyhav dua li cov pawg placebo tom qab 20 lub lis piam tab sis tsis tau muaj kev txhim kho hauv tag nrho cov roj, LDL, HDL, lossis triglycerides.

Qhov tseeb, kev noj tshuaj ntau dua ntawm alpha-lipoic acid tau muab rau tag nrho cov roj (cholesterol) thiab LDL ntau ntxiv hauv cov koom nrog kev kawm.

 

Daim tawv nqaij Hnub Ci

Tshuaj pleev ib ce tuam txhab feem ntau nyiam khav tias lawv cov khoom tau txais txiaj ntsig zoo "los tiv thaiv kev laus" lub zog ntawm alpha-lipoic acid. Kev tshawb fawb qhia tau tias yuav muaj qee qhov kev lees paub rau cov neeg foob no. Tshawb xyuas tsab xov xwm sau tseg tias nws yog cov tshuaj tiv thaiv muaj zog thiab tau kawm txog nws txoj kev tiv thaiv kev tiv thaiv kev tiv thaiv hluav taws xob.

 

Alpha Lipoic Acid (ALA) (1077-28-7) siv?

Alpha-lipoic acid los yog ALA yog lub zog tshwm sim uas ib txwm muaj nyob hauv lub cev. Nws pabcuam tseem ceeb rau kev ua haujlwm ntawm qib theem ntawm lub cev, xws li kev tsim hluav taws xob. Raws li koj nyob zoo, lub cev muaj peev xwm tsim tau txhua ALA nws xav tau rau cov laj thawj no. Dua li ntawm qhov tseeb ntawd, tau muaj ntau yam tsis ntev los no ntawm kev siv ALA tshuaj pab. Cov neeg tawm tswv yim ntawm ALA ua cov lus tshaj tawm uas muaj txiaj ntsig zoo los kho cov mob xws li mob ntshav qab zib thiab HIV kom ua kom yuag poob.

 

Alpha Lipoic Acid (ALA) (1077-28-7) ntau npaum

Thaum pom tias muaj kev nyab xeeb, tsis muaj ib qho kev qhia txog kev siv qhov tsim nyog ntawm alpha-lipoic acid. Feem ntau cov tshuaj tiv thaiv qhov ncauj tau muag hauv cov qauv xws li 100 txog 600 mg. Raws li qhov loj ntawm cov pov thawj tam sim no, qhov siab tshaj plaws niaj hnub noj ntau dua li 1,800 mg yog qhov ua rau muaj kev nyab xeeb rau cov neeg laus.

Nrog qhov tau hais los no, txhua yam ntawm lub cev qhov hnyav thiab hnub nyoog rau lub siab ua haujlwm thiab lub raum ua haujlwm tuaj yeem cuam tshuam dab tsi muaj kev nyab xeeb rau koj uas yog tus neeg. Raws li txoj cai ntawm tus ntiv tes xoo, yuam kev ntawm kev ceev faj thiab ib txwm xaiv rau qhov qis qis dua.

Alpha lipoic acid pabcuam ntawm nomtswv tuaj yeem pom online thiab hauv ntau lub khw muag khoom noj khoom haus kho mob thiab tsev muag tshuaj. Rau qhov siab tshaj plaws, cov tshuaj yuav tsum tau ua rau ntawm lub plab khoob.

 

Alpha-lipoic Acid hmoov kev muag khoom(Qhov Twg Yuav Alpha-lipoic Acid hmoov nyob hauv ntau)

Peb lub tuam txhab txaus siab rau kev sib raug zoo ntev nrog peb cov neeg vim tias peb tsom mus rau cov neeg siv khoom thiab muab cov khoom zoo. Yog tias koj txaus siab rau peb cov khoom lag luam, peb yoog tau nrog kho kom haum cov kev txiav txim siab kom haum koj cov kev xav tau tshwj xeeb thiab peb lub sijhawm ceev ceev ntawm kev txiav txim tau lees tias koj yuav tau saj zoo peb cov khoom kom raws sijhawm. Peb kuj tseem tsom rau kev pabcuam ntxiv tus nqi. Peb muaj nyob rau cov lus nug kev pabcuam thiab cov ntaub ntawv los txhawb koj txoj kev lag luam.

Peb yog tus kws tshaj lij Alpha-lipoic Acid hmoov tsum rau ntau xyoo, peb muab cov khoom lag luam nrog cov nqi sib tw, thiab peb cov khoom yog qhov ua tau zoo tshaj plaws thiab yauv mus kuaj kev ywj pheej, kom ntseeg tau tias nws muaj kev nyab xeeb rau noj thoob ntiaj teb.

 

References

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  3. Schupke, H; Hempel, R; Peter, G; Hermann, R; li al. (Lub Rau Hli 2001). “Cov teeb meem metabolic tshiab ntawm alpha-lipoic acid”. Tshuaj thiab Kev Tsim Txom. 29 (6): 855–62. PMID 11353754.
  4. Acker, DS; Wayne, WJ (1957). "Kev nquag thiab radioactive lip-lipoic acids". Phau ntawv xov xwm ntawm haiv neeg American Chemical Society. 79 (24): 6483–6487. doi: 10.1021 / ja01581a033.
  5. Hornberger, CS; Heitmiller, RF; Cov Phom Siv, IC; Schnakenberg, GHF; li al. (Xyoo 1952). “Cov hluavtaws ua haujlwm ntawm lipoic acid”. Phau ntawv xov xwm ntawm haiv neeg American Chemical Society. 74 (9): 2382. doi: 10.1021 / ja01129a511.