Anandamide (AEA) ntxiv rau (94421-68-8) Chaw Tsim Tshuaj - Cofttek

Anandamide (AEA) (94421-68-8)

Plaub Hlis Ntuj 7, 2020

Anandamide, tseem hu ua N-arachidonoylethanolamine lossis AEA, yog ib hom fatty acid neurotransmitter muab los ntawm cov tsis muaj kabmob ntawm eicosatetraenoic acid (arachidonic acid) qhov tseem ceeb an-6 polyunsaturated fatty acid.

 


raws li txoj cai: Hauv Pawg Ntau Lawm
Chav: 1kg / hnab, 25kg / Nruas

Anandamide (AEA) (94421-68-8) video

 

Anandamide (AEA) Specifications

 

Lub npe: Anandamide (AEA)
CAS: 94421-68-8
purity 50% hmoov ; 85% roj
Cov mis qauv: C22H37NO2
Lub cev nyhav: 361.526 g / mol
Melt Point: -4.8 ° C
Tshuaj lub npe: N-Arachidonoyl-2-hydroxyethylamide
txhais: Anandamide; AEA; Arachidonylethanolamide; Arachidonoyl ethanolamide.
Qhov tseem ceeb hauv InChI: LIGWYLOEDYSMTP-DOFZRALJSA-N
Ib nrab neej: N / A
Dej Cev: Soluble hauv DMSO, Methanol, Dej
Cia Kev Mob: 0 - 4 C rau lub sij hawm luv (hnub rau lis piam), lossis -20 C rau lub sij hawm ntev (hli)
daim ntawv thov: Txij li thaum Anandamide (AEA) coj los ua ke hauv thaj chaw ntawm lub paj hlwb qhov twg nco, kev txhawb zog, kev nkag siab thiab kev tswj hwm kev txav mus los, nws tuaj yeem cuam tshuam cov kev mob ntawm lub cev xws li mob, tswj kev xav, txaus siab thiab nqi zog.
tsos: lub teeb daj hmoov

 

Anandamide (AEA) CAS 94421-68-8 yog dab tsi?

Anandamide, tseem hu ua N-arachidonoylethanolamine lossis AEA, yog ib hom fatty acid neurotransmitter muab los ntawm qhov tsis-oxidative metabolism ntawm eicosatetraenoic acid (arachidonic acid) qhov tseem ceeb ω-6 polyunsaturated fatty acid. Lub npe tau muab los ntawm Sanskrit lo lus ananda, uas txhais tau tias "kev xyiv fab, paj tawg, zoo siab", thiab amide. Nws yog cov tshuaj los ntawm N-arachidonoyl phosphatidylethanolamine los ntawm ntau txoj hauv kev. Nws yog feem cuam tshuam feem ntau ntawm cov roj fatty amide hydrolase (FAAH) enzyme, uas hloov anandamid.

 

Anandamide (AEA) CAS 94421-68-8 cov txiaj ntsig

Anandamide (AEA) yog coj los ua ke enzymatically hauv thaj chaw ntawm lub hlwb uas tseem ceeb hauv kev nco, kev xav thiab tswj kev txav. Kev tshawb fawb qhia tau tias anandamide ua lub luag haujlwm hauv kev tsim thiab tawg ntawm lub sijhawm luv sib txuas ntawm cov leeg hlwb, thiab qhov no cuam tshuam nrog kev kawm thiab cim xeeb. Kev tshawb fawb tsiaj qhia tias ntau dhau lawm anandamide induces tsis nco qab. Qhov no qhia tau tias yog tias cov tshuaj yeeb dej caw tuaj yeem tsim kho uas ua rau anandamide los ntawm kev khi rau nws lub receptor, cov no yuav raug siv los kho kev nco ploj lossis tseem txhim kho kev nco uas twb muaj lawm!

 

Anandamide (AEA) CAS 94421-68-8 Mechanism Ntawm Kev Ua?

Anandamide, tseem hu ua N-arachidonoylethanolamine (AEA), yog ib qho kev ua kom muaj roj fatty acids neurotransmitter muab los ntawm cov tshuaj tiv thaiv tsis muaj kabmob ntawm eicosatetraenoic acid (arachidonic acid), qhov tseem ceeb omega-6 fatty acid. Lub npe tau muab los ntawm Sanskrit lo lus ananda, uas txhais tau tias "kev xyiv fab, bliss, zoo siab", thiab amide. Nws yog cov tshuaj los ntawm N-arachidonoyl phosphatidylethanolamine los ntawm ntau txoj hauv kev.

 

Anandamide (AEA) CAS 94421-68-8 Daim ntawv thov

Anandamide (AEA) coj los ua ke hauv thaj chaw ntawm lub hlwb qhov twg nco, kev txhawb zog, cov txheej txheem kev nkag siab zoo dua thiab kev tswj hwm txav tau tswj hwm. Nyob rau hauv txoj kev no, nws cuam tshuam rau lub nruab zog xws li mob, kev tswj hwm kev xav, txaus siab thiab nqi zog.

 

Anandamide (AEA) hmoov kev muag khoom(Qhov twg yuav Anandamide (AEA) hmoov hauv qhov ntau)

Peb lub tuam txhab txaus siab rau kev sib raug zoo ntev nrog peb cov neeg vim tias peb tsom mus rau cov neeg siv khoom thiab muab cov khoom zoo. Yog tias koj txaus siab rau peb cov khoom lag luam, peb yoog tau nrog kho kom haum cov kev txiav txim siab kom haum koj cov kev xav tau tshwj xeeb thiab peb lub sijhawm ceev ceev ntawm kev txiav txim tau lees tias koj yuav tau saj zoo peb cov khoom kom raws sijhawm. Peb kuj tseem tsom rau kev pabcuam ntxiv tus nqi. Peb muaj nyob rau cov lus nug kev pabcuam thiab cov ntaub ntawv los txhawb koj txoj kev lag luam.

Peb yog tus kws tshaj lij Anandamide (AEA) hmoov muab khoom siv tau ntau xyoo, peb muab cov khoom lag luam nrog cov nqi sib tw, thiab peb cov khoom yog qhov ua tau zoo tshaj plaws thiab yauv mus kuaj kev ywj pheej, kom ntseeg tau tias nws muaj kev nyab xeeb rau noj thoob ntiaj teb.

 

References

  • Cui HJ, Liu S, Yang R, Fu GH, Lu Y. N-stearoyltyrosine tiv thaiv thawj cortical neurons tiv thaiv oxygen-glucose deprivation-induced apoptosis los ntawm inhibiting anandamide inactivation system. Neurosci Res. 2017 Lub Tsib Hlis 9. pii: S0168-0102 (17) 30012-3. doi: 10.1016 / j.neures.2017.04.019. [Epub ua ntej sau] PubMed PMID: 28499834.
  • King-Himmelreich TS, Möser CV, Wolters MC, Schmetzer J, Schreiber Y, Ferreirós N, Russe OQ, Geisslinger G, Niederberger E. AMPK pab txhawb rau kev tawm dag zog ua kom lub cev tawm ntawm cov tshuaj endocannabinoids. Neuropharmacology. 2017 Lub Tsib Hlis 4. pii: S0028-3908 (17) 30198-3. doi: 10.1016 / j.neuropharm.2017.05.002. [Epub ua ntej sau] PubMed PMID: 28479394.
  • Pirone A, Lenzi C, Briganti A, Abbate F, Levanti M, Abramo F, Miragliotta V. Kev faib tawm ntawm cannabinoid receptor 1 thiab fatty acid amide hydrolase nyob rau hauv miv lub zes qe menyuam thiab oviduct. Lub Tebchaws Acta Histochem. 2017 Lub Tsib Hlis; 119 (4): 417-422. doi: 10.1016 / j.acthis.2017.04.007. Epub 2017 Lub Tsib Hlis 4. PubMed PMID: 28478955.