DAWB LUB HAIV NEEG

EGT
Lub cev metabolism hauv lub cev
EGT
Hnyav hlau ua qias tuaj
EGT
Cov pa phem
EGT
Tshuaj tua kab tsis huv
EGT
Ultraviolet hluav taws xob
EGT
Tshuaj tua kab tsis huv

DAWB LUB CAIJ & Cov teeb meem

Nquag, dawb radicals yog tsim nyog rau lub cev, tab sis cov dawb radicals ntau dhau tuaj yeem ua rau lub cev tsis txaus ntawm lub zog ua haujlwm, tom qab ntawd coj mus rau oxidative kev nyuaj siab hloov zuj zus hauv ntau yam kab mob (cov ntawv nyeem qhia tau tias dawb radicals yog qhov ntawm ntau yam kab mob).

(1) ↗

Cov neeg ntseeg siab tau

PubMed Central

Kev hwm cov ntaub ntawv los ntawm National Institutes of Health
Mus rau qhov chaw
EGT

TSO CAI

Peb lub cev tsis tuaj yeem ua haujlwm tsis muaj oxygen, thiab ib zaug muaj ntau cov dawb radicals ntau zog, lub cev nyob rau hauv oxidative kev ntxhov siab yuav ua rau kev kho kom ua tsis tiav hauv kev tshem tawm cov radicals dawb. Qee qhov tshwj xeeb, lub cev xav tau cov tshuaj tua kab mob antioxidant hauv vitro kom tshem tawm cov dawb radicals ntev dhau lawm.

(2) ↗

Cov neeg ntseeg siab tau

PubMed Central

Kev hwm cov ntaub ntawv los ntawm National Institutes of Health
Mus rau qhov chaw
Kev Loj Hlob Ntawm Cov Tshuaj Tiv Thaiv
EGT

L-KEV TXHAWJ XEEM A TSHIAB HOM TXUJ CI LOS TXHUA COV NTSEEG

EGT yog lub ntuj chiral amino-acid antioxidant biosynthesized hauv qee yam kab mob thiab hu ua fungi. Nws yog ib qho tseem ceeb bioactive compound uas tau siv los ua cov radical scavenger, ultraviolet ray lim, lub chaw tswj hwm ntawm oxidation-txo cov tshuaj tiv thaiv thiab cellular bioenergetics, thiab lub cev cytoprotector, thiab lwm yam.

L-Ergothioneine (EGT, ERGO, CAS: 497-30-3), tseem hu ua (S) -α-Carboxy-2,3-dihydro-N, N, N-trimethyl-2-thioxo-1H-imidazole- 4-ethanaminium sab hauv ntsev, tau pib tawm los ntawm ergot los ntawm Tanret C hauv xyoo 1909, tom qab ntawd nws tseem tau tshawb pom hauv cov ntshav tsiaj. Kev ntshiab EGT yog dawb siv lead ua, soluble hauv dej, (yaj 0.9mol / L ntawm chav sov). Autoxidation tsis tuaj yeem tshwm sim ntawm physiological pH tus nqi lossis hauv cov tshuaj alkaline muaj zog. EGT tuaj yeem muaj nyob hauv ob daim isomer - ib daim thiol thiab thione form, raws li qhia hauv qab no:

(3) ↗

Cov neeg ntseeg siab tau

PubMed Central

Kev hwm cov ntaub ntawv los ntawm National Institutes of Health
Mus rau qhov chaw
EGT

TXHEEJ TXHEEM

Nrog qhov zoo ntawm cov haujlwm ntau, EGT sawv ntawm ntau lwm cov antioxidants.

EGT
POM ZOO

Nrog rau qhov zoo ntawm ntau txoj haujlwm, EGT sawv tawm ntawm ntau lwm yam antioxidants.Qhov zoo (piv nrog glutathione, cysteine ​​thiab lwm yam):
——EGEG yuav yooj yim rau cov hlwb thiab cov concentration ntau dua ruaj khov lwm cov tshuaj tiv thaiv kab mob.
——EGEG zoo dua rau kev txo qis kev tuag ntawm tes los ntawm pyrogallol.
——EGT tsuas yog scavenges ROS kom tiv thaiv oxidation, thaum glutathione thiab lwm tus tau scavenge dawb radicals, uas yog, lwm yam antioxidants scavenge oxidation cov khoom.(1) Oleoylethanolamide (oea) - uas yog kev ua khawv koob hauv koj lub neej

EGT

COMPARISON NTAWM COV TXHEEJ TXHEEM

tau: EGT tau tshaj tawm kev nquag ntawm cov dawb radicals piv rau cov tshuaj tiv thaiv antioxidant li GSH, uric acid thiab trolox. Hauv tshwj xeeb, lub siab tshaj plaws cov tshuaj tiv thaiv antioxidant muaj peev xwm nthuav tawm los ntawm EGT vs. peroxyl radicals ua rau 25% siab dua tus nqi tau txais nrog kev siv antioxidant trolox. Qhov muaj peev xwm sib ntawm EGT rau hydroxyl radicals yog 60% siab dua, piv rau cov uric acid, uas sawv cev rau kev siv antioxidant thiab hydroxyl radicals. Thaum kawg, EGT pom tias muaj cov tshuaj tiv thaiv antioxidant ntau tshaj plaws rau peroxynitrite, nrog qhov muaj peev xwm faib 10% siab dua li ntawm uric acid.

EGT

LWM LUB LAUS

EGT kuj tseem muaj qhov cuam tshuam los tswj kev siv lub zog nyob hauv intracellular,

txhim kho kev tiv thaiv,

txhim kho cov ciaj sia taus ntawm phev,

tiv thaiv daim siab los ntawm kev raug mob,

inhibiting mob,

tshuaj neurodegeneration,

kev loj hlob tsis xws luag thiab mob cataract.

KEV KOOM SIAB KEV LAG LUAM

G EGT TAU TXOJ CAI RAU YOOJ YIM HAIV NEEG RAU YAM THIAB TSIAJ
EGT
EGT
EGT
STR QHIA

5-10mg ib pawg rau cov neeg laus thiab 2-3 units txuas ntxiv noj haus yog qhov tseem ceeb hauv koj kev noj zaub mov txhua hnub.

Tau qhov twg los: Li Yiqun, Zhou Nianbo. Kev Ua Yeeb Yam Ib Ce thiab Kev Siv EGT [J]. Khoom Noj Khoom Haus Engineering , 2010,9 (3) : 26-28.

(4) ↗

Cov neeg ntseeg siab tau

PubMed Central

Kev hwm cov ntaub ntawv los ntawm National Institutes of Health
Mus rau qhov chaw

Cov nkag tau muaj npe raws li hauv qab no:

Cov menyuam yaus (3-11 xyoos)L 0 mg / hnub
Cov Hluas (11-21 xyoos)≤30 mg / hnub
Cov Neeg Loj (21-80 xyoo)≤30 mg / hnub
Nco tseg: 1. Kev noj tshuaj rau menyuam yaus thiab cov neeg laus (3 -80 xyoo) 2.Siv rau cov poj niam cev xeeb tub lossis lactating tsis pom zoo.

Cov ntaub ntawv peev txheej: Tetrahedron thaum thov rau Asmeskas NDI

Cov ntaub ntawv hais qhia: 10.5mg / g rau OXIS's ADI (Txais Tau Txais Txhua Hnub).

(6) ↗

Cov neeg ntseeg siab tau

PubMed Central

Kev hwm cov ntaub ntawv los ntawm National Institutes of Health
Mus rau qhov chaw
Y SYNTHESIS
EGT

TSHAWB & UA NTAWV

(1) NTXHUAB

Tam sim no, muaj peb txoj hauv kev rau cov khoom EGT: hluavtaws ua haujlwm, tej yam ntuj tso tso xyoob tawm (feem ntau yog los ntawm nceb, tsiaj cov nqaij thiab ntshav ntxiv), thiab txoj kev siv tshuaj tua kab mob biosynthesis

Kev sib piv ntawm EGT Extraction Methods

EGT
(2) DAIM NTAWV THOV

EGT muaj cov ntawv thov dav dav hauv cov tshuaj pleev ib ce, tej zaub mov, tshuaj lag luam, tshuaj kho mob, biomedicine, thiab lwm yam.

EGT
(3) LWM YAM KEV TSIM NYOG
EGT

References

  1. Oleoylethanolamide (oea) - uas yog tej yam hauv koj lub neej
  2. Anandamide vs cbd: uas ib qho zoo dua rau koj li kev noj qab haus huv? Txhua yam koj yuav tsum paub txog lawv!
  3. Txhua yam koj xav paub txog nicotinamide riboside chloride
  4. Magnesium l-threonate pabcuam ntawm nomtswv: cov txiaj ntsig, noj ntau npaum li cas, thiab cov tshwm sim tshwm sim
  5. Palmitoylethanolamide (pea): cov txiaj ntsig, siv ntau npaum li cas, siv, ntxiv
  6. Sab 6 cov txiaj ntsig kev noj qab haus huv ntawm cov tshuaj resveratrol
  7. Cov txiaj ntsig sab saum toj ntawm kev noj phosphatidylserine (ps)
  8. Cov txiaj ntsig sab saum toj 5 ntawm kev noj pyrroloquinoline quinone (pqq)
  9. Qhov zoo tshaj plaws nootropic ntxiv ntawm alpha gpc
  10. Qhov zoo tshaj tawm los tiv thaiv kev laus ntawm nicotinamide mononucleotide (nmn)

Dr. Zeng Zhaosen

CEO & FOUNDER

Co-founder, lub tuam txhab qhov kev tswj hwm qhov tseem ceeb ua haujlwm; PhD tau txais los ntawm Fudan University hauv organic chemistry. Ntau tshaj li cuaj xyoo ntawm cov kev paub hauv cov organic synthesis teb cov kws tshuaj. Kev nplua nuj dhau los hauv kev sib xyaw ua ke, kev siv tshuaj lom neeg thiab cov khoom siv tshuaj lom neeg thiab kev ua kom zoo nkauj kev tswj hwm.

Hu rau kuv tam sim no